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    What component of sugarless gum can cause diarrhea?

    Question #101273. Asked by edmund80. (Nov 26 08 12:11 AM)


    krzys44

    		sorbitol

    http://www.foxnews.com/story/0,2933,321992,00.html

    Nov 26 08, 1:07 AM
    edmund80

    		Yes, sorbitol is the culprit in chewing gum diarrhea.

    http://www.springerlink.com/content/jk1140t45715h221/

    Which should not be surprising as there was a time when sorbitol and other non-absorbable carbohydrates like mannitol and lactulose were used for bowel cleansing prior to colonoscopy. They have fallen out of favor with the occurrence of the unfortunately named but very real phenomenon of colonic gas explosion, which is due to hydrogen gas production by bacterial fermentation of these non-absorbable carbohydrates (with an electrosurgical procedure as the spark for the explosion).

    http://www.uptodate.com/patients/content/topic.do?topicKey=~fC9E3rU_upmsz9
    http://www.wjgnet.com/1007-9327/13/5295.pdf
    http://www.ncbi.nlm.nih.gov/pubmed/17632809



    Nov 26 08, 2:21 PM

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