I've got some, I know the minute I post this I'll think of a million more. These quotes might not be 100% accurate, but they are close enough!
"Ask him what he likes to eat, if he says p****, invite him over!" and "You told me to keep him busy, he's busy holding his nuts!"--both quotes by Kyra Sedgewick in Something to Talk About.
"I'm not crazy, I've just been in a very bad mood for the last 40 years." and "Yeah, I'm sure he's a gentleman, I bet he takes the dishes outta the sink before he pees in it." --both by Shirley MacLaine in Steel Magnolias.
"The sleeper has awakened." --Dune
The entire Twinkie conversation in Ghostbusters (the original one,I think!)
"I never wanted to be a razor so bad in my life." --Brendan Fraser in With Honors.
"What would you prefer, yellow spandex?"--X-Men.
"I so need lesson from you on how to be cool. Tell me the part about Kenny G again."--Alicia Silverstone in Clueless.
"You are small. S, M, all."--Cannonball Run.
In Dogma when Chris Rock is talking about Jesus, the whole scene.
"Do you like apples? I got her number, how do you like them apples?"--Matt Damon in Good Will Hunting.
"While they did live happily ever after. The point, gentleman, is that they lived."--Ever After.
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"Step in my transporter, so I can teleport you all around my heavenly body." --Jamiroquai "Cosmic Girl"