It's not the only monosyllabic number, or the only number with 4 letters, or the only number with a 'v'. It's not a palindrome or an anagram. There doesn't appear to be anything special about the word "five". Unless you're referring to:
Drop the "f" and "e" and you have the roman numeral for 4. Half of 'five' is 4.
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Obama-Biden '08!