Basic Organic Chemistry

15 Points Per Correct Answer - No time limit  

1. Which of the following types of reactions involves R-X, Li, CuI, and R'-X? Grignard synthesis Clemmenson Reduction Corey-Posner , Whitesides-House synthesis Friedel-Crafts Alkylation

2. In the type of reaction involving R-X, Li, CuI, and R'-X?; R'-X must NOT be which of the following? Secondary cycloalkyl Primary Tertiary Methyl

3. Grignard reagents react with ketones to form which of the following? Primary alcohols Tertiary alcohols Secondary alcohols Carboxylic acids

4. Which of the following is a Huckel number? 8 16 12 10

5. Which of the following are reagents used in the nitration of benzene? Conc. HNO3 and conc. H2SO4 Ammonia Dilute solutions of NO3 and H2SO4 Concentrated NO3

6. Which of the following is NOT associated with oxidation? PCC LiAlH4 Jones Reagent Hot KMnO4

7. Which of the following will reduce an aldehyde but not a carboxylic acid? LiAlH4 NaBH4 H2, Pt catalyst PCC

8. If branching of the side chain in the product is a problem in Friedel-Crafts alkylation, how can a product with an unbranched side chain be reached? It can't--the more stable carbocation cannot be avoided Friedel-Crafts acylation followed by Clemmenson reduction Treat the product with a strong acid Use Cl2 instead of AlCl3

9. A methyl group on benzene is considered which of the following? Ortho-para director, activating Meta director, activating Ortho-para director, deactivating Meta director, deactivating

10. When an alcohol is exposed to an acid, what is the first thing that always happens? An acid-base reaction Protonation of the hydroxyl group A double bond forms It becomes a diol