1. King George III was known as Farmer George and also as Mad King George. Historical documents detailing his symptoms clearly indicate that his intermittent episodes of madness were caused by which disease? Phenylketonuria Schizophrenia Porphyria Azotemia

2. King Henry VIII is famous for dispensing with his wives. For many years it was generally, but erroneously, believed that the inability of his wives to provide him with numerous heirs was because Henry suffered from a sexually transmitted disease. Which one? Chlamydia Herpes Gonorrhoea Syphilis

3. This famous patient suffered from deafness which started when he was about 27 and got progressively worse until he was totally deaf by middle age. Yet it did not stop him from becoming one of the greatest composers of all time. Who was this patient? Mozart Beethoven Wagner Strauss

4. At the Battle of Copenhagen, Admiral Parker, doubting the success of the British attack on the Danish Fleet, signalled Horatio Nelson to disengage. Nelson put his telescope to his blind eye and declared he could not see the signal. By ignoring the order, he turned a potential defeat into a victory. Why was Nelson blind in his right eye? Severe cataract War wound (metal splinters in the eye) Chronic glaucoma A tumour of the right optic nerve

5. Why was Napoleon defeated at Waterloo? The battle was lost for a variety of reasons but one reason was his health. Napoleon was suffering from a severe case of what? Prolapsed piles (haemorrhoids) Malaria Acute bladder infection Epilepsy

6. Winston Churchill was the British Prime Minister during most of the Second World War. In September, 1945, it became apparent that he had a medical condition which necessitated surgery the following year. What was this condition? Gallstones Hernia Gangrenous little finger Appendicitis

7. John Fitzgerald Kennedy was the 35th President of the USA. The fact that he suffered from a hormonal disorder was covered up because to admit to it would have caused his political opponents to claim he was not capable of performing the presidential duties. Which disorder did he have? Graves' disease Cushing's syndrome Addison's disease Hashimoto's disease

8. Franklin Delano Roosevelt was the 32nd President of the USA. For the last 23 years of his life, including the whole of his time in the White House, he was not able to walk unaided. He was crippled as a result of contracting which disease? Muscular dystrophy Meningitis Motor neurone disease Poliomyelitis

9. Grigory Novykh, better known as Rasputin, was a Siberian peasant who gained the trust of the Nicholas II, the last Russian czar, and his family and thus contributed to the downfall of the Russian empire. He was able to exert an influence on them because of his ability to help relieve the symptoms of a disease suffered by Nicholas and Alexandra’s son, Alexis. From which disease did Alexis suffer? Spina bifida Muscular dystrophy Haemophilia Cystic fibrosis

10. Hitler was one of the most evil men in world history. Was there a medical cause contributing to his uncontrollable rages, psychotic behaviour and depravity? There have been many theories but perhaps the most plausible is that he was a drug addict. To which drug was Hitler addicted? Amphetamines Opium Cocaine Morphine