12. Until 2016, this city was the largest North American city that had teams in only 3 of the 4 major US sports leagues - MLB, NBA, NFL, NHL.
Note: large metro areas are counted as one city, so LA-Anaheim, are counted as one city
From Quiz Cities and their Teams
Answer:
Los Angeles
This was the biggest surprise in making this quiz - LA did not have a team in the NFL until 2016. They have two in the other other sports and even in MLS. But not in the NFL, until the Rams moved there from St. Louis; though they did have in the past: the Rams (until 1994) and the Raiders (1982-1994), were in LA in the past and even the San Diego Chargers started in LA, but left in 1963 until they returned in 2017.