The value of 2^66 is 73,786,976,294,838,206,464, and the number 78 is the final two-digit number (from 10 to 99) to appear within the sequence of the powers of 2. In recreational mathematics, this is a famous trivia fact regarding how numbers manifest within exponential expansions. If you scan the digits of the powers of 2 (2^0, 2^1, 2^2, ...) looking for two-digit substrings, you will find that 89 out of the 90 possible two-digit numbers show up early on. The number 78 is the lone holdout. When you reach 2^66 78 finally appears for the very first time (as the third and fourth digits: 737869...). This completes the entire set of two-digit numbers from 10 to 99.
The table below shows the last five two-digit numbers to make their debut in the powers of 2 sequence, along with the specific power where they first appear:
Two-Digit Power of Full value of
Number 2 (2^n) Power of 2
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22 2^43 8,796,093,022,208
66 2^46 70,368,744,177,664
50 2^52 4,503,599,627,370,496
61 2^58 288,230,376,151,711,744
78 2^66 73,786,976,294,838,206,464