- Kyiv was officially established in 482 CE, but archaeological evidence of large-scale human settlements in the area dates all the way back to 4300 BCE.
- Kharkiv was a major target of the Northeastern Ukraine offensive in Russia's invasion of Ukraine that began in February 2022.
- Odesa was one of the chief centers of the Russian Revolution of 1905 and was the scene of the mutiny on the warship Potemkin.
- Dnipro is home to the largest Jewish cemetery in Europe, which covers an area of over 8 hectares (about 20 acres).
- Lviv has manufactured the traditional Ukrainian musical instrument, the "bandura", since 1948.
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