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Quiz about Canine Genetic Disorders
Quiz about Canine Genetic Disorders

Canine Genetic Disorders Trivia Quiz


How much do you know about the inherited maladies that can plague man's best friend? This quiz covers both genetic disorders and methods of preventing them.

A multiple-choice quiz by crisw. Estimated time: 7 mins.
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Author
crisw
Time
7 mins
Type
Multiple Choice
Quiz #
102,090
Updated
Dec 03 21
# Qns
25
Difficulty
Tough
Avg Score
14 / 25
Plays
8946
Awards
Top 5% quiz!
Last 3 plays: ZWOZZE (14/25), jhchance (12/25), skatersarehott (10/25).
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Question 1 of 25
1. Only purebred dogs have problems with genetic disorders.


Question 2 of 25
2. This disorder, found most often in the Bedlington terrier, is also known as Wilson's disease. Hint


Question 3 of 25
3. Found in many breeds, especially large ones, this is the most common inherited skeletal problem in dogs. Hint


Question 4 of 25
4. Found primarily in small breeds, but also in a few larger breeds such as the flat-coated retriever, this skeletal abnormality is also known as "slipping kneecaps." Hint


Question 5 of 25
5. This genetic abnormality is most common in white dogs. Hint


Question 6 of 25
6. Which of the following breeds does NOT have a high incidence of genetically-associated cancers? Hint


Question 7 of 25
7. This breed is subject to a genetic eye disorder that includes inadequate development of the blood vessels that nourish the retina, clefts in the optic disc, and retinal detachment. The effects on the dog range from no symptoms to blindness. Hint


Question 8 of 25
8. Perhaps the most common genetic eye defect in dogs has the acronym PRA. What does this stand for? Hint


Question 9 of 25
9. This is the most common endocrine system disorder in large-breed dogs. Hint


Question 10 of 25
10. This inherited bleeding disorder, named for the physician who discovered it, is found in many breeds of dogs. Hint


Question 11 of 25
11. This heart defect, most commonly seen in Newfoundlands and golden retrievers, can cause sudden death in an otherwise healthy dog. Hint


Question 12 of 25
12. This disorder, most commonly seen in the Doberman pinscher and Great Dane, causes weakness and incoordination of the legs, starting with the rear legs and gradually progressing to total paralysis. Hint


Question 13 of 25
13. We are all familiar with seeing tiny dogs- often white toy poodles or Maltese- that tremble continuously. Is this caused by a genetic disorder?


Question 14 of 25
14. The most common inherited liver disorder in dogs is an abnormality of blood flow in the liver that leads to slow growth, neurological signs, vomiting, diarrhea and kidney stones. What is this disorder? Hint


Question 15 of 25
15. This disfiguring skin disorder affects Shetland sheepdogs and collies. The skin, especially on the face, tail tip, elbows, hips and toes, can be crusty, blistered and ulcerated, often resulting in permanent scarring. The underlying muscles can also be affected, causing atrophy. Hint


Question 16 of 25
16. Which of these breeds is subject to the most genetic disorders? Hint


Question 17 of 25
17. Now let's move on to how to prevent these disorders from occurring. First of all, is this a true statement?- If you wish to acquire a dog that is free of genetic disorders, then you are probably better off getting a purebred from someone who is just breeding one litter from their purebred but unregistered non-show dogs than from a breeder with show dogs, because the show dogs are likely to be inbred and have more problems.


Question 18 of 25
18. Many pet stores sell puppies with guarantees against genetic disorders. These guarantees are helpful in ensuring a healthy pup.


Question 19 of 25
19. One of the best ways to prevent genetic disorders is to screen the parent dogs to make sure that they are free of heritable problems. In the United States, one registry that records dogs free of specific diseases is the Orthopedic Foundation for Animals (OFA). For which disorders does OFA maintain databases of disease-free dogs? Hint


Question 20 of 25
20. At what age will OFA certify a dog as being free of hip dysplasia? Hint


Question 21 of 25
21. What US organization tracks dogs that are free of hereditary eye defects? Hint


Question 22 of 25
22. What hereditary defect can be detected by BAER testing? Hint


Question 23 of 25
23. What defects are detected by use of a Holter monitor? Hint


Question 24 of 25
24. When you are buying a dog just to be a pet, health testing is not important.


Question 25 of 25
25. If you are planning on acquiring a purebred dog, which of the following should you do? Hint



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quiz
Quiz Answer Key and Fun Facts
1. Only purebred dogs have problems with genetic disorders.

Answer: False

Most disorders are found in mixed breeds as well. If a dog inherits the correct genes for expression of a disorder, it will have that disorder, purebred or not.
2. This disorder, found most often in the Bedlington terrier, is also known as Wilson's disease.

Answer: Copper toxicosis

This error in copper metabolism causes toxic levels of copper to accumulate in the liver. Liver biopsies can detect the disorder.
3. Found in many breeds, especially large ones, this is the most common inherited skeletal problem in dogs.

Answer: Hip dysplasia

A malformation of the hip joint, hip dysplasia can produce signs varying from absence of symptoms to crippling arthritis. The disorder cannot be cured, but expensive surgery can help prevent further joint damage.
4. Found primarily in small breeds, but also in a few larger breeds such as the flat-coated retriever, this skeletal abnormality is also known as "slipping kneecaps."

Answer: Patellar luxation

Patellar luxation can be treated by surgery that deepens the patellar groove so that the kneecap does not dislocate.
5. This genetic abnormality is most common in white dogs.

Answer: Deafness

Some breeds with high incidences of genetic congenital deafness include the Dalmatian (about 30% are deaf in one or both ears), English Setter, Australian Cattle Dog and Bull Terrier.
6. Which of the following breeds does NOT have a high incidence of genetically-associated cancers?

Answer: Beagle

Although cancer is the leading medical-related cause of death in dogs, beagles have a fairly low rate of cancer. The other three breeds have markedly higher rates of cancers. Over 80% of all deaths of flat-coated retrievers are caused by cancers of various types, especially hemangiosarcoma; a mutation in the p53 gene which normally suppresses tumor growth is suspected. Bernese mountain dogs have a very high rate of histiocytosis. Boxers have a high incidence of mast cell tumors, lymphomas and other cancers.
7. This breed is subject to a genetic eye disorder that includes inadequate development of the blood vessels that nourish the retina, clefts in the optic disc, and retinal detachment. The effects on the dog range from no symptoms to blindness.

Answer: Collie

This disorder is known as collie eye anomaly. Other related breeds, such as the border collie and Shetland sheepdog, may also have this condition.
8. Perhaps the most common genetic eye defect in dogs has the acronym PRA. What does this stand for?

Answer: Progressive retinal atrophy

PRA disorders of several types are common in many breeds, including Irish setters, Siberian huskies, miniature schnauzers, golden retrievers, borzois and cocker spaniels. In all of these disorders, the retina degenerates. In some forms, this occurs early in the dog's life; in some forms it occurs late. This degeneration leads to total blindness.
9. This is the most common endocrine system disorder in large-breed dogs.

Answer: Hypothyroidism

Several breeds, including the golden retriever and Doberman pinscher, have a high rate of hypothyroidism. Symptoms include lethargy, poor haircoat, dry skin, behavioral changes, and intolerance to cold. It can be treated with thyroid hormone replacement.
10. This inherited bleeding disorder, named for the physician who discovered it, is found in many breeds of dogs.

Answer: von Willebrand's disease

This disorder usually causes only mild symptoms, if any. Although affected dogs may have lengthened bleeding times and experience some problems such as nosebleeds, the disease is usually not serious. Affected breeds include the Doberman pinscher, Shetland sheepdog and golden retriever.
11. This heart defect, most commonly seen in Newfoundlands and golden retrievers, can cause sudden death in an otherwise healthy dog.

Answer: Aortic stenosis

This disorder causes narrowing of the aorta, the main artery to the heart. This can lead to changes in the electrical rhythms of the heart that can cause sudden death. Some dogs will also show symptoms of heart failure.
12. This disorder, most commonly seen in the Doberman pinscher and Great Dane, causes weakness and incoordination of the legs, starting with the rear legs and gradually progressing to total paralysis.

Answer: Wobbler syndrome

Also known as cervical vertebral instability, this disorder results from abnormalities in the neck vertebrae that lead to compression of the spinal cord.
13. We are all familiar with seeing tiny dogs- often white toy poodles or Maltese- that tremble continuously. Is this caused by a genetic disorder?

Answer: Yes

This is known as "shaker dog syndrome" or "little white shaker syndrome" and is usually seen in very small white dogs. Surprisingly, Valium is an effective treatment for many affected dogs.
14. The most common inherited liver disorder in dogs is an abnormality of blood flow in the liver that leads to slow growth, neurological signs, vomiting, diarrhea and kidney stones. What is this disorder?

Answer: Portosystemic shunt

PSS can be corrected by surgery. Affected breeds include Yorkshire terriers, miniature schnauzers and Irish wolfhounds.
15. This disfiguring skin disorder affects Shetland sheepdogs and collies. The skin, especially on the face, tail tip, elbows, hips and toes, can be crusty, blistered and ulcerated, often resulting in permanent scarring. The underlying muscles can also be affected, causing atrophy.

Answer: Dermatomyositis

Some dogs recover, although they may bear disfiguring scars. Others, especially those with muscular involvement, have so much damage to the facial region that they cannot eat or drink.
16. Which of these breeds is subject to the most genetic disorders?

Answer: German shepherd

German shepherds are subject to over 100 genetic disorders, some found in no other breed. Some of the German-shepherd specific disorders include footpad softness, focal spinal muscular atrophy, giant axonal neuropathy, lumbosacral vertebral stenosis and juvenile hyperparathyroidism.

Some of the disorders found almost exclusively in the German shepherd include degenerative myelopathy, perianal fistulas, glycogen storage disease type III, pannus, exocrine pancreatic insufficiency, small intestinal bacterial overgrowth with immunoglobulin A deficiency, hemivertebra, masticatory muscle myositis and pituitary dwarfism.

Some disorders with a high incidence in German shepherds include epilepsy, hip dysplasia, myasthenia gravis and elbow dysplasia.
17. Now let's move on to how to prevent these disorders from occurring. First of all, is this a true statement?- If you wish to acquire a dog that is free of genetic disorders, then you are probably better off getting a purebred from someone who is just breeding one litter from their purebred but unregistered non-show dogs than from a breeder with show dogs, because the show dogs are likely to be inbred and have more problems.

Answer: No

Show breeders are far more likely to be knowledgeable breeders that health-test their dogs. In addition, it is impossible to trace the genetic lineage of non-registered dogs.
18. Many pet stores sell puppies with guarantees against genetic disorders. These guarantees are helpful in ensuring a healthy pup.

Answer: False

In almost all cases, the "guarantees" are good for only one year. Most genetic disorders show up later in the dog's life. Due to poor breeding practices, pet store pups are a case of genetic Russian roulette.
19. One of the best ways to prevent genetic disorders is to screen the parent dogs to make sure that they are free of heritable problems. In the United States, one registry that records dogs free of specific diseases is the Orthopedic Foundation for Animals (OFA). For which disorders does OFA maintain databases of disease-free dogs?

Answer: All of these

Although it was started as a registry to record dogs free of hip dysplasia, OFA has expanded to record dogs free of other disorders as well, including elbow dysplasia, patellar luxation, cardiac disorders, hypothyroidism, craniomandibular osteopathy and Legg-Calve-Perthes disease.
20. At what age will OFA certify a dog as being free of hip dysplasia?

Answer: 2 years

Vets submit x-rays of the dog's hips, taken in specified positions, to OFA. Only dogs free of dysplasia are assigned an OFA rating of Fair, Good or Excellent and are given an OFA number.
21. What US organization tracks dogs that are free of hereditary eye defects?

Answer: CERF

CERF stands for Canine Eye Registry Foundation. Dogs can obtain CERF clearance from certified veterinary opthalmologists beginning at age 6 months. Clearance must be renewed every year.
22. What hereditary defect can be detected by BAER testing?

Answer: Deafness

BAER stands for "Brainstem Auditory Evoked Response." In this painless test, young puppies have electrodes attached to the skin of their heads that can record brain waves caused by detection of sound. Deaf puppies will show no sound-activated brain waves.
23. What defects are detected by use of a Holter monitor?

Answer: Heart rhythm irregularities

A Holter monitor consists of electrocardiogram leads that are attached to the dog's chest and a small pack containing a tape recorder that records the dog's heart rhythms for an extended period. This can detect irregularities that occur sporadically that would not be detected in a one-time test.
24. When you are buying a dog just to be a pet, health testing is not important.

Answer: False

On the contrary! A good pet must be healthy! Don't be dissuaded- when you are looking for a dog, demand health testing!
25. If you are planning on acquiring a purebred dog, which of the following should you do?

Answer: All of these

Become an educated buyer! Learn what tests are recommended for your breed and don't buy from a breeder who does not test. OFA and CERF databases are searchable online. We can prevent many of the terrible tragedies of canine genetic disorders- but only if we educate ourselves!
Source: Author crisw

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